Title
Adversarial Time-to-Event Modeling.
Abstract
Modern health data science applications leverage abundant molecular and electronic health data, providing opportunities for machine learning to build statistical models to support clinical practice. Time-to-event analysis, also called survival analysis, stands as one of the most representative examples of such statistical models. We present a deep-network-based approach that leverages adversarial learning to address a key challenge in modern time-to-event modeling: nonparametric estimation of event-time distributions. We also introduce a principled cost function to exploit information from censored events (events that occur subsequent to the observation window). Unlike most time-to-event models, we focus on the estimation of time-to-event distributions, rather than time ordering. We validate our model on both benchmark and real datasets, demonstrating that the proposed formulation yields significant performance gains relative to a parametric alternative, which we also propose.
Year
Venue
DocType
2018
ICML
Conference
Volume
ISSN
Citations 
abs/1804.03184
Proceedings of the 35th International Conference on Machine Learning, PMLR 80:735-744, 2018
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Paidamoyo Chapfuwa121.04
Chenyang Tao287.93
Chunyuan Li346733.86
Courtney Page400.34
Benjamin Goldstein501.01
L. Carin64603339.36
Ricardo Henao728623.85