Title | ||
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Integrated microRNA and mRNA expression profile analysis of tumor-associated macrophages after exposure to single-dose irradiation. |
Abstract | ||
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We established a murine model irradiated with a single dose of 25 Gy that could initiate temporal changes in the expression of miRNAs associated with cell proliferation and the immune response, as evidenced by macrophages directly extracted from irradiated tumors after two weeks of IR. Statistical analyses were conducted by comparing the miRNA expression in macrophages from non-irradiated versus irradiated tumors. Thus, our study could lead to a better understanding of the function of miRNA expressions, which changed temporally in an irradiated tumor microenvironment. |
Year | DOI | Venue |
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2018 | 10.1016/j.compbiolchem.2018.03.016 | Computational Biology and Chemistry |
Keywords | Field | DocType |
Tumor-associated macrophages,Tumor microenvironment,Microarray,microRNA,microRNA target interaction (MTI) | Tumor microenvironment,Tumor progression,Microarray,Biology,microRNA,Cancer research,Radiation therapy,Immune system,Bioinformatics,Cancer,Gene expression profiling | Journal |
Volume | ISSN | Citations |
74 | 1476-9271 | 0 |
PageRank | References | Authors |
0.34 | 1 | 7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Wei-Hsiang Kung | 1 | 1 | 0.96 |
Andy Chi-Lung Lee | 2 | 0 | 0.34 |
Chi-dung Yang | 3 | 84 | 4.79 |
Ching-Fang Yu | 4 | 1 | 0.96 |
Men-Yee Chiew | 5 | 17 | 1.44 |
Fang-Hsin Chen | 6 | 1 | 1.30 |
Hsien-Da Huang | 7 | 835 | 63.83 |