Paper Info
Title
DExSI: a new tool for the rapid quantitation of 13C-labelled metabolites detected by GC-MS.
Abstract
Stable isotope directed metabolomics is increasingly being used to measure metabolic fluxes in microbial, plant and animal cells. Incorporation of C-13/N-15 isotopes into a wide range of metabolites is typically determined using gas chromatography-mass spectrometry (GC/MS) or other hyphenated mass spectrometry approaches. The DExSI (Data Extraction for Stable Isotope-labelled metabolites) pipeline is an interactive graphical software package which can be used to rapidly quantitate isotopologues for a wide variety of metabolites detected by GC/MS. DExSI performs automated metabolite annotation, mass and positional isotopomer abundance determination and natural isotope abundance correction. It provides a range of output options and is suitable for high throughput analyses.
Year
DOI
Venue
2018
10.1093/bioinformatics/bty025
BIOINFORMATICS
Field
DocType
Volume
Computer science,Gas chromatography–mass spectrometry,Bioinformatics,Chromatography
Journal
34
Issue
ISSN
Citations 
11
1367-4803
0
PageRank 
References 
Authors
0.34
3
2
Name
Order
Citations
PageRank
Michael J. Dagley100.34
Malcolm J. McConville2535.57