Name
Title | ||
|---|---|---|
Determination of tumor marker carcinoembryonic antigen with biosensor based on optical quantum weak measurements |
Abstract | ||
|---|---|---|
A phase-sensitive weak measurement biosensor was proposed for the detection of carcinoembryonic antigen (CEA), one common category of tumor markers. The total internal reflection (TIR) at the interface of the prism without precious metal coating was exploited to introduce the phase delay between horizontal and vertical polarizations, which can be determined through the central wavelength shift of output spectra for the sensing of the refractive index of the sample. In the weak measurement analysis, the specific binding reaction of tumor markers with a refractive index change on the surface of the prism can be monitored in real time through the central wavelength shift. With the specific absorption measurement, the feasibility of this weak measurement-based biosensor was experimentally demonstrated. We provide a low cost and convenient approach for tumor marker detection. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.3390/s18051550 | SENSORS |
Keywords | Field | DocType |
phase measurement,optical biosensor,weak measurement,total internal reflection | Analytical chemistry,Total internal reflection,Group delay and phase delay,Carcinoembryonic antigen,Biosensor,Engineering,Optoelectronics,Tumor marker,Absorption (pharmacology),Refractive index,Weak measurement | Journal |
Volume | Issue | ISSN |
18 | 5.0 | 14248220 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
10 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Guan Tian | 1 | 1 | 4.34 |
| Wang Xiangnan | 2 | 0 | 0.68 |
| Dongmei Li | 3 | 12 | 4.43 |
| Zhang Yilong | 4 | 1 | 2.38 |
| Yonghong He | 5 | 5 | 4.54 |
| Shi Lixuan | 6 | 0 | 0.34 |
| Liu Yiqing | 7 | 0 | 0.34 |
| Yang Yuxuan | 8 | 0 | 0.34 |
| Yang Xu | 9 | 118 | 41.02 |
| Cui Rui | 10 | 0 | 0.34 |