Paper Info
Title
Multi-Pinhole Based X-Ray Fluorescence Computed Tomography: A Comparison With Single Pinhole Case
Abstract
An x-ray fluorescence computed tomography using a pinhole collimator (p-XFCT) for medical use depicts the 3-D distribution of imaging agent by collecting the x-ray fluorescence photons emitted from the imaging agent accumulated in an organ using a pinhole collimator and a 2-D detector. However, the number of the fluorescent x-ray photons are restricted by the pinhole, leading to acquisition of low S/N projections due to the photon starvation. Simultaneous acquisition of multiple projections using a multi-pinhole scheme overcomes the photon starvation. In this research, we clarified the measurement process and described the quantitative linear relationship between the quantities to be estimated and to be measured. We solved the multi-pinhole based XFCT (mp-XFCT) as a linear inverse problem regarding the described measurement process using ML-EM (maximum likelihood expectation-maximization) algorithm. We actually constructed an mp-XFCT imaging system at beamline AR-NE7A in KEK, and performed imaging experiment using a physical phantom to demonstrate the efficacy of mp-XFCT.
Year
DOI
Venue
2018
10.1007/978-3-319-94211-7_23
IMAGE AND SIGNAL PROCESSING (ICISP 2018)
Keywords
Field
DocType
X-ray fluorescence, Computed tomography, Pinhole, Molecular imaging
Beamline,Computer vision,Molecular imaging,Photon,Collimator,Computer science,Imaging phantom,Optics,Artificial intelligence,Inverse problem,Detector,Performed Imaging
Conference
Volume
ISSN
Citations 
10884
0302-9743
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Tenta Sasaya100.68
Naoki Sunaguchi203.04
Seung-Jun Seo300.34
Tsutomu Zeniya401.35
Kazuyuki Hyodo554.21
Jongki Kim622.05
Tetsuya Yuasa753.87