Title
Gene Expression for Simulation of Biological Tissue
Abstract
BioDynaMo is a biological processes simulator developed by an international community of researchers and software engineers working closely with neuroscientists. The authors have been working on gene expression, i.e. the process by which the heritable information in a gene - the sequence of DNA base pairs - is made into a functional gene product, such as protein or RNA. Typically, gene regulatory models employ either statistical or analytical approaches, being the former already well understood and broadly used. In this paper, we utilize analytical approaches representing the regulatory networks by means of differential equations, such as Euler and Runge-Kutta methods. The two solutions are implemented and have been submitted for inclusion in the BioDynaMo project and are compared for accuracy and performance.
Year
DOI
Venue
2018
10.1109/WAINA.2018.00092
2018 32nd International Conference on Advanced Information Networking and Applications Workshops (WAINA)
Keywords
Field
DocType
gene expression,Differential equation,BioDynaMo
Differential equation,RNA,Gene,Gene expression,Gene product,Euler's formula,Software,Artificial intelligence,Computational biology,Base pair,Mathematics,Machine learning
Conference
ISBN
Citations 
PageRank 
978-1-5386-5396-8
0
0.34
References 
Authors
16
5
Name
Order
Citations
PageRank
Sadyk Sayfullin100.34
Fedor Akhmetov200.34
Manuel Mazzara349364.05
Ruslan Mustafin41107.86
Víctor Rivera55212.94