Paper Info
Title
Handedness-dependent functional organizational patterns within the bilateral vestibular cortical network revealed by fMRI connectivity based parcellation.
Abstract
Current evidence points towards a vestibular cortex that involves a multisensory bilateral temporo-parietal-insular network with a handedness-dependent hemispheric lateralization. This study aimed to identify handedness-dependent organizational patterns of (lateralized and non-lateralized) functional subunits within the human vestibular cortex areas. 60 healthy volunteers (30 left-handed and 30 right-handed) were examined on a 3T MR scanner using resting state functional MRI (fMRI). The data was analyzed in four major steps using a functional connectivity based parcellation (fCBP) approach: (1) independent component analysis (ICA) on a whole brain level to identify different resting state networks (RSN); (2) creation of a vestibular informed mask from four whole brain ICs that included reference coordinates of the vestibular network extracted from meta-analyses of vestibular neuroimaging experiments; (3) Re-ICA confined to the vestibular informed mask; (4) cross-correlation of the activated voxels within the vestibular subunits (parcels) to each other (P-to-P) and to the whole-brain RSN (P-to-RSN).
Year
DOI
Venue
2018
10.1016/j.neuroimage.2018.05.018
NeuroImage
Keywords
Field
DocType
Vestibular cortical network,Asymmetry,Multisensory,Hemisphere dominance,Functional parcellation,Lateralization
Insula,Brain mapping,Neuroscience,Lateralization of brain function,Vestibular system,Resting state fMRI,Psychology,Cognitive psychology,Vestibular cortex,Sensory system,Superior temporal gyrus
Journal
Volume
ISSN
Citations 
178
1053-8119
3
PageRank 
References 
Authors
0.42
13
7
Name
Order
Citations
PageRank
Valerie Kirsch1796.21
Rainer Boegle241.51
D Keeser3252.44
E. Kierig430.42
Birgit Ertl-Wagner550.83
Thomas Brandt614416.15
Marianne Dieterich7628.68