Name
Abstract | ||
|---|---|---|
We demonstrate a novel feedback mechanism to implement closed loop neuromodulation based on a combination of electrical and chemical neural signal recording. The platform consists of our custom designed multi-channel amplifier for recording electrical and chemical signals (such as pH), data processing unit and the stimulator IC unit. A novelty of our approach is that the neural chemical signals are used to initiate stimulation and electrical compound action potentials (CAPs) to determine stimulation dosage. The proposed adaptive stimulation platform has been implemented in the context of Vagus Nerve Stimulation (VNS) for obesity therapy. The demonstration is based on externally generated signals derived from our in vivo experiments on physiological stimulation of the gastric branch of vagus nerve by injection of gut hormone cholecystokinin (CCK). |
Year | DOI | Venue |
|---|---|---|
2017 | 10.1109/BIOCAS.2017.8325100 | 2017 IEEE Biomedical Circuits and Systems Conference (BioCAS) |
Keywords | Field | DocType |
closed loop neuromodulation,dual mode biosignals,electrical signal recording,chemical neural signal recording,multichannel amplifier,electrical signals,data processing unit,stimulator IC unit,neural chemical signals,electrical compound action potentials,adaptive stimulation platform,physiological stimulation,Vagus nerve stimulation | Biomedical engineering,Vagus nerve stimulation,Computer science,Vagus nerve,Electronic engineering,Neuromodulation,Medical treatment,Cholecystokinin,Stimulation,Amplifier | Conference |
ISBN | Citations | PageRank |
978-1-5090-5804-4 | 0 | 0.34 |
References | Authors | |
0 | 7 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Khalid B. Mirza | 1 | 0 | 2.70 |
| Krzysztof Wildner | 2 | 0 | 0.34 |
| Nishanth Kulasekeram | 3 | 0 | 0.68 |
| Simon Cork | 4 | 1 | 1.05 |
| Stephen R. Bloom | 5 | 0 | 1.01 |
| Konstantin Nikolic | 6 | 26 | 8.09 |
| Christofer Toumazou | 7 | 265 | 59.06 |