Abstract | ||
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Clinical proton and ions beams for cancer treatment provide maximum energy deposition (Bragg Peak, BP) at the end of their range and practically no dose behind. This enables a more efficient therapeutic option comparing with classical photon-based radiotherapy where maximum energy deposition occurs at the body/tissues interface. Obviously, optimum/minimum-error BP detection and calibration is thus a key aspect of this treatment. This work investigates a promising detection technique, based on the so called (proton) iono-acoustic effect. The BP energy deposition causes a small (mK) heating of the surrounding region that in turn induces a pressure variation. This propagates an ultrasound signal (MHz range) whose time-of-flight measurement aims to detect the BP position with very high accuracy (u003c1mm). This paper presents the simulation results of complete mixed-signals and mixed-energies model that starting from proton beam energy calculates the induced pressure variation in water, emulates the propagation of sound waves in the medium and finally provides a voltage signal (including noise) whose time evolution determines BP position. |
Year | Venue | Field |
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2017 | BioCAS | Photon,Proton,Analog front-end,Computer science,Voltage,Optics,Electronic engineering,Bragg peak,Time evolution,Beam (structure),Calibration |
DocType | Citations | PageRank |
Conference | 0 | 0.34 |
References | Authors | |
0 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Michele Riva | 1 | 1 | 0.96 |
Elia Arturo Vallicelli | 2 | 1 | 1.98 |
A. Baschirotto | 3 | 176 | 54.55 |
Marcello De Matteis | 4 | 42 | 17.29 |