Name
Title | ||
|---|---|---|
Integration of electrical, structural, and anatomical imaging for the guidance of cardiac resynchronization therapy |
Abstract | ||
|---|---|---|
Background: Placing the left ventricular (LV) lead at a site of late electrical activation remote from scar is desired for cardiac resynchronization therapy (CRT) response. Objective: The purpose of this study was to integrate electrocardiographic imaging (ECGi) with computed tomography (CT) derived coronary venous anatomy and delayed enhancement cardiac magnetic resonance imaging (DE-CMR) derived scar to reconstruct a pre-procedural roadmap for LV lead guidance in CRT. Methods: Three CRT candidates with focal scar defined by DE-CMR were prospectively included. Intrinsic body surface potentials measurements (BSPM) were carried out. Inverse reconstruction using the CT heart-torso geometry were used for ECGi. Meshes of the CT coronary veins, epicardium with ECGi activation times, and DE-CMR scar were integrated. Results: The ECGi-CT-CMR roadmap was used for CRT implantation in 2/3 patients. Placing the LV lead remote from scar was accomplished in 2/2 patients. Target veins from the ECGi-CT-CMR roadmap were located in a region of 80-105 ms electrical delay. Conclusion: ECGi-CT-CMR roadmaps can be used during CRT implantation to guide LV lead placement to a coronary vein remote from scar in a region of late electrical activation, possibly improving CRT. |
Year | DOI | Venue |
|---|---|---|
2017 | 10.22489/CinC.2017.044-466 | 2017 Computing in Cardiology (CinC) |
Keywords | Field | DocType |
ECGi-CT-CMR roadmap,CRT implantation,coronary vein remote,electrical imaging,anatomical imaging,left ventricular lead,cardiac resynchronization therapy response,electrocardiographic imaging,lead guidance,CRT candidates,focal scar,intrinsic body surface potentials measurements,CT heart-torso geometry,CT coronary veins,ECGi activation times,DE-CMR scar,LV lead remote,electrical delay,structural imaging,late electrical activation,computed tomography derived coronary venous anatomy,delayed enhancement cardiac magnetic resonance imaging derived scar,preprocedural roadmap,inverse reconstruction,time 80.0 ms to 105.0 ms | Lead Placement,Computed tomography,Cardiac magnetic resonance imaging,Radiology,Cardiac resynchronization therapy,Medicine,Coronary Vein | Conference |
Volume | ISSN | ISBN |
44 | 2325-8861 | 978-1-5386-4555-0 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
10 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Uyen Chau Nguyen | 1 | 0 | 0.68 |
| Matthijs J M Cluitmans | 2 | 2 | 2.42 |
| Casper Mihl | 3 | 0 | 0.34 |
| Justin J. G. Luermans | 4 | 0 | 0.34 |
| Bas L. J. H. Kietselaer | 5 | 0 | 0.34 |
| Sebastiaan C. A. M. Bekkers | 6 | 0 | 0.34 |
| Suzanne Gommers | 7 | 0 | 0.34 |
| Paul G A Volders | 8 | 8 | 4.86 |
| Frits W Prinzen | 9 | 17 | 3.73 |
| Kevin Vernooy | 10 | 1 | 1.06 |