Title
Learning From Weakly-Labeled Clinical Data For Automatic Thyroid Nodule Classification In Ultrasound Images
Abstract
This paper proposes a semi-supervised learning method based on weakly-labeled data to automatically classify ultrasound (US) thyroid nodules. Key to our new approach is the unification of multi-instance learning (MIL) with deep learning. Benefiting from that, our method can directly use off-the-shelf clinical data, which involves no labels to indicate nodule classes. To this end, we take the US images of a patient as a bag, and take the corresponding pathology report as the bag label. Specifically, we first propose a bag generating method, wherein the detected thyroid nodules are considered as instances corresponding to certain bag. After that, we design an effective EM algorithm to train a convolutional neural network (CNN) for nodule classification. We conduct extensive experiments and comprehensive evaluations on different datasets, and all the experiments confirm that, our method significantly outperforms state-of-the-art MIL algorithms, which exhibits great potential in clinical applications.
Year
Venue
Keywords
2018
2018 25TH IEEE INTERNATIONAL CONFERENCE ON IMAGE PROCESSING (ICIP)
Weakly-labeled data, Multi-instance learning (MIL), Convolutional neural network (CNN), Thyroid ultrasound image, Automatic nodule classification
Field
DocType
ISSN
Pattern recognition,Computer science,Convolutional neural network,Expectation–maximization algorithm,Medical imaging,Feature extraction,Artificial intelligence,Deep learning,Thyroid nodules,Ultrasonic imaging,Ultrasound
Conference
1522-4880
Citations 
PageRank 
References 
0
0.34
0
Authors
6
Name
Order
Citations
PageRank
Jianxiong Wang100.34
Shuai Li217531.37
Wenfeng Song395.22
Hong Qin42120184.31
Bo Zhang500.34
Aimin Hao618340.57