Paper Info
Title
Granger Causality To Reveal Functional Connectivity In The Mouse Basal Ganglia-Thalamocortical Circuit
Abstract
In this study we analyze simultaneously recorded spike trains at several levels of the basal ganglia-thalamocortical circuit in freely moving parvalbumin (PV)-deficient and wildtype (WT) (i.e., expressing PV at normal levels) mice. Parvalbumin is a Calcium-binding protein, mainly expressed in GABAergic inhibitory neurons, that affects the dynamics of the Excitatory/Inhibitory balance at the network level. We apply Granger causality analysis in order to measure the functional connectivity of different selected brain areas and their possible alterations due to PV depletion. Our results show that connections between ventromedial prefrontal cortex and Nucleus Accumbens are not affected by PV depletion.
Year
DOI
Venue
2018
10.1007/978-3-030-01421-6_38
ARTIFICIAL NEURAL NETWORKS AND MACHINE LEARNING - ICANN 2018, PT II
Keywords
Field
DocType
Basal ganglia-thalamocortical circuit, Nucleus accumbens, Spike train analysis, Granger causality
Ventromedial prefrontal cortex,GABAergic,Neuroscience,Parvalbumin,Pattern recognition,Nucleus accumbens,Computer science,Granger causality,Excitatory postsynaptic potential,Inhibitory postsynaptic potential,Artificial intelligence,Basal ganglia
Conference
Volume
ISSN
Citations 
11140
0302-9743
0
PageRank 
References 
Authors
0.34
6
4
Name
Order
Citations
PageRank
Alessandra Lintas111.03
Takeshi Abe231.80
Alessandro E . P. Villa334853.26
Yoshiyuki Asai4307.56