Name
Abstract | ||
|---|---|---|
We are currently building the PET/X scanner, which is a breast positron emission tomography (PET) scanner combined with a standard X-ray mammography system. The role for the PET/X scanner is to precisely measure changes in radiotracer uptake after an initial test dose of adjuvant or neoadjuvant therapy. The system performance target is that a measured 20% change in tracer uptake in 5 mm diameter lesions with standardized uptake value (SUV) of 5 g/ml should correspond to at least 95% specificity (<5% false positive rate for detecting a true change in uptake). Simulations indicate that this performance can be achieved with a 3-minute scan of a 370-MBq (10-mCi) injection of 18F-FDG or other radiotracers.The PET scanner consists of 4 planar detectors, forming a rectangular system with complete azimuthal angular sampling (around the z-axis). The panels are formed of detector blocks each using a 20x20 array of LYSO scintillation crystals (2x2x10mm(3)) coupled to a 12x12 array of 3x3 mm(2) pixel silicon photomultipliers (SiPMs). The overall system size is 24cm wide (6 blocks) by 16cm deep (4 blocks axially) by 4-to-12cm adjustable height.The PET system mounts on a mammography scanner by swapping out the standard 'bucky' unit. Patients are scanned in both mammography and PET modes without movement to allow co-registration of the two image sets. Here, we review the system design, construction, and initial performance measures. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1117/12.2318419 | 14TH INTERNATIONAL WORKSHOP ON BREAST IMAGING (IWBI 2018) |
Keywords | Field | DocType |
Quantitative imaging, Molecular imaging, Multimodality imaging, System design | Biomedical engineering,Standardized uptake value,Mammography,Silicon photomultiplier,Positron emission tomography,Pixel,Scanner,Lyso-,Detector,Materials science | Conference |
Volume | ISSN | Citations |
10718 | 0277-786X | 0 |
PageRank | References | Authors |
0.34 | 0 | 8 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| MacDonald, Lawrence | 1 | 1 | 0.76 |
| William C. J. Hunter | 2 | 0 | 0.34 |
| Chengeng Zeng | 3 | 0 | 0.34 |
| Larry A. Pierce | 4 | 0 | 0.34 |
| Sergei Dolinski | 5 | 0 | 0.34 |
| Donald DeWitt | 6 | 0 | 0.34 |
| Robert S. Miyaoka | 7 | 0 | 0.34 |
| Paul E. Kinahan | 8 | 104 | 19.98 |