Title
Improved enzyme annotation with EC-specific cutoffs using DETECT v2.
Abstract
We present DETECT v2-an enzyme annotation tool which considers the effect of sequence diversity when assigning enzymatic function [as an Enzyme Commission (EC) number] to a protein sequence. In addition to capturing more enzyme classes than the previous version, we now provide EC-specific cutoffs that greatly increase precision and recall of assignments and show its performance in the context of pathways. Availability and implementation: https://github. com/ParkinsonLab/DETECT-v2
Year
DOI
Venue
2018
10.1093/bioinformatics/bty368
BIOINFORMATICS
Field
DocType
Volume
Data mining,Annotation,Computer science
Journal
34
Issue
ISSN
Citations 
19
1367-4803
0
PageRank 
References 
Authors
0.34
5
5
Name
Order
Citations
PageRank
Nirvana Nursimulu100.34
Leon L. Xu200.34
James Wasmuth3643.65
Ivan Krukov400.34
John Parkinson500.68