Name
Abstract | ||
|---|---|---|
High molecular weight cell-free DNA (hmw cfDNA) found in biological fluid, such as blood, is a promising biomarker for cancer detection. Due to the abundance of background apoptotic cell-free DNA in blood, quantifying the native concentration of hmw cfDNA using existing methods is technically challenging, time consuming, and expensive. We have developed a novel technology which utilizes Alternating Current Electrokinetics (ACE) to isolate hmw cfDNA directly from blood. Furthermore, we integrated this technology into a handheld device which utilizes a smartphone for power, instruction transmission, optical detection, image processing, and data transmission. The detection of hmw cfDNA in blood plasma demonstrated the performance of the device. We are continuing development of this device as a future point of care in vitro diagnostic. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1109/EMBC.2018.8513553 | EMBC |
Field | DocType | Volume |
Biomedical engineering,Computer vision,Point of care,Computer science,DNA,Cancer detection,Artificial intelligence | Conference | 2018 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
8 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Robert Turner | 1 | 83 | 4.23 |
| James Madsen | 2 | 0 | 0.34 |
| Pedro David Simon Herrera | 3 | 0 | 0.34 |
| John Wallace | 4 | 0 | 0.34 |
| Jonathan Madrigal | 5 | 0 | 0.34 |
| Juan Pablo Hinestrosa | 6 | 0 | 0.34 |
| Irina Dobrovolskaia | 7 | 0 | 0.34 |
| Rajaram Krishnan | 8 | 0 | 0.34 |