Name
Title | ||
|---|---|---|
Endogenous Fluorescence Lifetime Imaging (FLIM) Endoscopy For Early Detection Of Oral Cancer And Dysplasia. |
Abstract | ||
|---|---|---|
We have performed a pilot clinical study, in which multispectral endogenous fluorescence (or autofluorescence) lifetime imaging (FLIM) was performed on clinically suspicious oral lesions of 73 patients undergoing tissue biopsy for oral dysplasia and cancer diagnosis. The results from this pilot study indicated that mild-dysplasia and early stage oral cancer could be detected from benign lesions using a computed aided diagnosis system developed based on biochemical and metabolic biomarkers derived from the endogenous FLIM images. The diagnostic performance of this novel FLIM clinical tool was estimated using a leave-onepatient-out cross-validation approach, which reported levels of sensitivity >90%, specificity >85%, and Area Under the Receiving Operating Curve (ROC-AUC) >0.9. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1109/EMBC.2018.8513027 | EMBC |
Field | DocType | Volume |
Computer vision,Fluorescence-lifetime imaging microscopy,Computer science,Endoscopy,Biopsy,Autofluorescence,Dysplasia,Biomarker (medicine),Artificial intelligence,Radiology,Oral Dysplasia,Cancer | Conference | 2018 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
10 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Javier A Jo | 1 | 3 | 4.10 |
| Shuna Cheng | 2 | 0 | 0.34 |
| Rodrigo Cuenca-Martinez | 3 | 0 | 0.34 |
| Elvis Duran-Sierra | 4 | 0 | 0.34 |
| Bilal Malik | 5 | 0 | 1.01 |
| Beena Ahmed | 6 | 78 | 20.09 |
| Kristen Maitland | 7 | 0 | 0.68 |
| Yi-Shing Lisa Cheng | 8 | 0 | 0.34 |
| John Wright | 9 | 0 | 1.35 |
| Terry Reese | 10 | 0 | 1.35 |