Title
Coronary Calcium Detection using 3D Attention Identical Dual Deep Network Based on Weakly Supervised Learning.
Abstract
Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of coronary calcium detection. However, manual efforts are time and resource consuming and even impracticable to be applied on large-scale cohorts. In this paper, we propose the attention identical dual network (AID-Net) to perform CAC detection using scan-rescan longitudinal non-contrast CT scans with weakly supervised attention by only using per scan level labels. To leverage the performance, 3D attention mechanisms were integrated into the AID-Net to provide complementary information for classification tasks. Moreover, the 3D Gradient-weighted Class Activation Mapping (Grad-CAM) was also proposed at the testing stage to interpret the behaviors of the deep neural network. 5075 non-contrast chest CT scans were used as training, validation and testing datasets. Baseline performance was assessed on the same cohort. From the results, the proposed AID-Net achieved the superior performance on classification accuracy (0.9272) and AUC (0.9627).
Year
DOI
Venue
2019
10.1117/12.2512541
Proceedings of SPIE
Keywords
DocType
Volume
3D grad-cam,attention,CAC,coronary artery calcium,AID-Net
Conference
10949
ISSN
Citations 
PageRank 
0277-786X
0
0.34
References 
Authors
0
9
Name
Order
Citations
PageRank
Yuankai Huo19626.45
James G. Terry211.04
Jiachen Wang311.38
Vishwesh Nath4245.95
Camilo Bermudez5323.09
Shunxing Bao6468.53
Prasanna Parvathaneni7406.94
J. Jeffrey Carr800.34
Bennett A. Landman970074.20