Name
Abstract | ||
|---|---|---|
Molecularly imprinted polymers (MIPs) are high affinity robust synthetic receptors, which can be optimally synthesized and manufactured more economically than their biological equivalents (i.e. antibody). In MIPs production, rational design based on molecular modeling is a commonly employed technique. This mostly aids in (i) virtual screening of functional monomers (FMs), (ii) optimization of monomer-template ratio, and (iii) selectivity analysis. We present MIRATE, an integrated science gateway for the intelligent design of MIPs. By combining and adapting multiple state-of-the-art bioinformatics tools into automated and innovative pipelines, MIRATE guides the user through the entire process of MIPs' design. The platform allows the user to fully customize each stage involved in the MIPs' design, with the main goal to support the synthesis in the wetlaboratory. Availability: MIRATE is freely accessible with no login requirement at http://mirate.di.univr.it/. All major browsers are supported. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1515/jib-2017-0075 | JOURNAL OF INTEGRATIVE BIOINFORMATICS |
Keywords | Field | DocType |
docking,molecularly imprinted polymers,science gateway | Molecularly imprinted polymer,Data mining,Computer architecture,Computer science,Science gateway,Rational design | Journal |
Volume | Issue | ISSN |
15 | SP4 | 1613-4516 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
9 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Mirko Busato | 1 | 1 | 0.71 |
| Rosario Distefano | 2 | 11 | 2.13 |
| Ferdia Bates | 3 | 0 | 0.34 |
| Kal Karim | 4 | 0 | 0.34 |
| Alessandra Maria Bossi | 5 | 0 | 0.68 |
| José Manuel López Vilariño | 6 | 0 | 0.34 |
| Sergey Piletsky | 7 | 0 | 1.35 |
| Nicola Bombieri | 8 | 318 | 38.74 |
| Alejandro Giorgetti | 9 | 6 | 1.64 |