Title
Path R-CNN for Prostate Cancer Diagnosis and Gleason Grading of Histological Images.
Abstract
Prostate cancer is the most common and second most deadly form of cancer in men in the United States. The classification of prostate cancers based on Gleason grading using histological images is important in risk assessment and treatment planning for patients. Here, we demonstrate a new region-based convolutional neural network (R-CNN) framework for multitask prediction using a Epithelial Network Head and a Grading Network Head. Compared to a single task model, our multi-task model can provide complementary contextual information, which contributes to better performance. Our model achieved stateof-the-art performance in epithelial cells detection and Gleason grading tasks simultaneously. Using five-fold cross-validation, our model achieved an epithelial cells detection accuracy of 99.07with an average AUC of 0.998. As for Gleason grading, our model obtained a mean intersection over union of 79.56an overall pixel accuracy of 89.40%.
Year
DOI
Venue
2019
10.1109/TMI.2018.2875868
IEEE transactions on medical imaging
Keywords
Field
DocType
Feature extraction,Image segmentation,Biomedical imaging,Glands,Prostate cancer,Solid modeling
Computer vision,Grading (education),Medical imaging,Convolutional neural network,Radiation treatment planning,Image segmentation,Artificial intelligence,Prostate cancer,Prostate,Radiology,Mathematics,Cancer
Journal
Volume
Issue
ISSN
38
4
1558-254X
Citations 
PageRank 
References 
3
0.43
0
Authors
8
Name
Order
Citations
PageRank
Wenyuan Li164.22
Jiayun Li2104.65
Karthik Sarma3112.98
King Chung Ho472.21
Shiwen Shen5344.42
Beatrice S. Knudsen641.13
Arkadiusz Gertych7884.95
Corey Arnold84112.22