Title
IMG/VR v.2.0: an integrated data management and analysis system for cultivated and environmental viral genomes.
Abstract
The Integrated Microbial Genome/Virus (IMG/VR) system v.2.0 (https://img.jgi.doe.gov/vr/) is the largest publicly available data management and analysis platform dedicated to viral genomics. Since the last report published in the 2016, NAR Database Issue, the data has tripled in size and currently contains genomes of 8389 cultivated reference viruses, 12 498 previously published curated prophages derived from cultivated microbial isolates, and 735112 viral genomic fragments computationally predicted from assembled shotgun metagenomes. Nearly 60% of the viral genomes and genome fragments are clustered into 110384 viral Operational Taxonomic Units (vOTUs) with two or more members. To improve data quality and predictions of host specificity, IMG/VR v.2.0 now separates prokaryotic and eukaryotic viruses, utilizes known prophage sequences to improve taxonomic assignments, and provides viral genome quality scores based on the estimated genome completeness. New features also include enhanced BLAST search capabilities for external queries. Finally, geographic map visualization to locate user-selected viral genomes or genome fragments has been implemented and download options have been extended. All of these features make IMG/VR v.2.0 a key resource for the study of viruses.
Year
DOI
Venue
2019
10.1093/nar/gky1127
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Genome,Gene,Biology,Prophage,Viral genomes,IMG,Genomics,Computational biology,Genetics,Data management
Journal
47
Issue
ISSN
Citations 
D1
0305-1048
1
PageRank 
References 
Authors
0.34
7
13
Name
Order
Citations
PageRank
A. David Páez-Espino121.36
Simon Roux211.02
I-Min A. Chen3458177.16
Krishna Palaniappan426922.76
Anna Ratner514311.04
Ken Chu624021.08
Marcel Huntemann71238.41
T B K Reddy811.02
Joan Carles Pons911.36
Mercè Llabrés1010412.98
Emiley A Eloe-Fadrosh1121.36
Natalia N Ivanova1220017.48
Nikos Kyrpides1339552.87