Title
Stemformatics: visualize and download curated stem cell data.
Abstract
Stemformatics is an established gene expression data portal containing over 420 public gene expression datasets derived from microarray, RNA sequencing and single cell profiling technologies. Developed for the stem cell community, it has a major focus on pluripotency, tissue stem cells, and staged differentiation. Stemformatics includes curated collections' of data relevant to cell reprogramming, as well as hematopoiesis and leukaemia. Rather than simply rehosting datasets as they appear in public repositories, Stemformatics uses a stringent set of quality control metrics and its own pipelines to process handpicked datasets from raw files. This means that about 30% of datasets processed by Stemformatics fail the quality control metrics and never make it to the portal, ensuring that Stemformatics data are of high quality and have been processed in a consistent manner. Stemformatics provides easy-to-use and intuitive tools for biologists to visually explore the data, including interactive gene expression profiles, principal component analysis plots and hierarchical clusters, among others. The addition of tools that facilitate cross-dataset comparisons provides users with snapshots of gene expression in multiple cell and tissues, assisting the identification of cell-type restricted genes, or potential housekeeping genes. Stemformatics is freely available at stemformatics.org.
Year
DOI
Venue
2019
10.1093/nar/gky1064
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Gene,Reprogramming,Biology,Stem cell,Profiling (computer programming),Download,Housekeeping gene,Computational biology,Genetics,Snapshot (computer storage),Gene expression profiling
Journal
47
Issue
ISSN
Citations 
D1
0305-1048
1
PageRank 
References 
Authors
0.37
0
9
Name
Order
Citations
PageRank
Jarny Choi131.49
Chris M. Pacheco230.86
Rowland Mosbergen310.37
Othmar Korn410.37
Tyrone Chen511.05
Isha Nagpal610.37
Steve Englart710.37
Paul W Angel810.37
Christine A Wells9131.99