Paper Info
Title
SIFTS: updated Structure Integration with Function, Taxonomy and Sequences resource allows 40-fold increase in coverage of structure-based annotations for proteins.
Abstract
The Structure Integration with Function, Taxonomy and Sequences resource (SIFTS; http://pdbe.org/sifts/) was established in 2002 and continues to operate as a collaboration between the Protein Data Bank in Europe (PDBe; http://pdbe.org) and the UniProt Knowledgebase (UniProtKB; http://uniprot.org). The resource is instrumental in the transfer of annotations between protein structure and protein sequence resources through provision of up-to-date residue-level mappings between entries from the PDB and from UniProtKB. SIFTS also incorporates residue-level annotations from other biological resources, currently comprising the NCBI taxonomy database, IntEnz, GO, Pfam, InterPro, SCOP, CATH, PubMed, Ensembl, Homologene and automatic Pfam domain assignments based on HMM profiles. The recently released implementation of SIFTS includes support for multiple cross-references for proteins in the PDB, allowing mappings to UniProtKB isoforms and UniRef90 cluster members. This development makes structure data in the PDB readily available to over 1.8 million UniProtKB accessions.
Year
DOI
Venue
2019
10.1093/nar/gky1114
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Biological classification,UniProt Knowledgebase,Biology,Taxonomy (biology),Computational biology,Protein Data Bank,Genetics,Peptide sequence,Protein structure
Journal
47
Issue
ISSN
Citations 
D1
0305-1048
2
PageRank 
References 
Authors
0.41
1
7
Name
Order
Citations
PageRank
Jose M. Dana120616.67
Aleksandras Gutmanas2201.20
Nidhi Tyagi320.75
Guoying Qi420.41
Claire O'Donovan551.20
Maria Jesus Martin62793365.41
Sameer Velankar731826.34