Abstract | ||
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•Oscillations-free closed-loop PID controlled drug delivery in neuromuscular blockade is considered.•Bifurcation analysis shows that oscillations can be avoided by properly adjusting the overall gain of the PID controller.•The time-varying gain neither affects the stability of the control system nor causes new nonlinear dynamical phenomena.•Two particle filters and Extended Kalman Filter are compared performance-wise on synthetic and real data from surgery room.•The particle filters perform better in terms of bias in the phases of surgery where the system output significantly varies. |
Year | DOI | Venue |
---|---|---|
2019 | 10.1016/j.cmpb.2016.07.025 | Computer Methods and Programs in Biomedicine |
Keywords | Field | DocType |
Closed-loop drug delivery,Nonlinear systems,Oscillations,Parameter estimation,Particle,Filters Wiener models | Neuromuscular Blockade,Extended Kalman filter,Control theory,Nonlinear system,PID controller,Control theory,Computer science,Control system,Estimation theory,Linearization | Journal |
Volume | ISSN | Citations |
171 | 0169-2607 | 0 |
PageRank | References | Authors |
0.34 | 0 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Alexander Medvedev | 1 | 72 | 22.43 |
Zhanybai T. Zhusubaliyev | 2 | 82 | 29.09 |
Olov Rosen | 3 | 23 | 4.10 |
Margarida Martins da Silva | 4 | 12 | 4.56 |