Title
Gene co-expression networks from RNA sequencing of dairy cattle identifies genes and pathways affecting feed efficiency.
Abstract
The present study provides new information on the biological functions in liver that are potentially involved in controlling feed efficiency. The hub genes and upstream regulators (ATP7b, IFNG and IL10RA) involved in these functions are potential candidate genes for the development of new biomarkers. However, the hub genes, upstream regulators and pathways involved in the co-expressed networks were different in both breeds. Hence, additional studies are required to investigate and confirm these findings prior to their use as candidate genes.
Year
DOI
Venue
2018
10.1186/s12859-018-2553-z
BMC Bioinformatics
Keywords
Field
DocType
Co-expressed genes,Dairy cattle,Feed efficiency,Holstein,Hub genes,Jersey,Pathways,RNA-seq,Residual feed intake
Gene,Biology,RNA-Seq,Feed conversion ratio,Residual feed intake,Regulator gene,Dairy cattle,Genetics,Reference genome,Background selection
Journal
Volume
Issue
ISSN
19
1
1471-2105
Citations 
PageRank 
References 
0
0.34
4
Authors
4
Name
Order
Citations
PageRank
S M Salleh100.34
G Mazzoni200.34
P. Løvendahl331.43
Haja N. Kadarmideen4383.15