Abstract | ||
---|---|---|
Longer-term growth experiments followed by whole genome sequencing and transcriptome analysis can provide a better understanding of conditional gene essentiality and mechanisms of adaptation to such perturbations. Compensatory mutations are largely reproducible mechanisms and are in agreement with genome-scale modeling predictions to loss of function gene deletion events. |
Year | DOI | Venue |
---|---|---|
2018 | 10.1186/s12918-018-0653-z | BMC Systems Biology |
Keywords | Field | DocType |
Adaptive evolution,Essentiality,Genome-scale model | Cognitive reframing,Gene,Biology,Gene knockout,Systems biology,Cell biology,Computational biology,Computational analysis,Isozyme | Journal |
Volume | Issue | ISSN |
12 | 1 | 1752-0509 |
Citations | PageRank | References |
0 | 0.34 | 7 |
Authors | ||
9 |
Name | Order | Citations | PageRank |
---|---|---|---|
Gabriela I Guzmán | 1 | 0 | 0.34 |
Connor A Olson | 2 | 0 | 0.68 |
Ying Hefner | 3 | 0 | 0.68 |
Patrick V Phaneuf | 4 | 2 | 1.38 |
Edward Catoiu | 5 | 4 | 1.46 |
Lais B Crepaldi | 6 | 0 | 0.34 |
Lucas Goldschmidt Micas | 7 | 0 | 0.34 |
Bernhard O. Palsson | 8 | 751 | 67.99 |
Adam M Feist | 9 | 27 | 3.15 |