Title
Confidence interval constraint based regularization framework for PET quantization.
Abstract
In this paper, a new generic regularized reconstruction framework based on confidence interval constraints for tomographic reconstruction is presented. As opposed to usual state-of-the-art regularization methods that try to minimize a cost function expressed as the sum of a data-fitting term and a regularization term weighted by a scalar parameter, the proposed algorithm is a two-step process. The first step concentrates on finding a set of images that relies on direct estimation of confidence intervals for each reconstructed value. Then, the second step uses confidence intervals as a constraint to choose the most appropriate candidate according to a regularization criterion. Two different constraints are proposed in this paper. The first one has the main advantage of strictly ensuring that the regularized solution will respect the interval-valued data-fitting constraint, thus preventing over-smoothing of the solution while offering interesting properties in terms of spatial and statistical bias/variance trade-off. Another regularization proposition based on the design of a smoother constraint also with appealing properties is proposed as an alternative. The competitiveness of the proposed framework is illustrated in comparison to other regularization schemes using analytical and GATE-based simulation and real PET acquisition.
Year
DOI
Venue
2019
10.1109/TMI.2018.2886431
IEEE transactions on medical imaging
Keywords
Field
DocType
Image reconstruction,Positron emission tomography,TV,Kernel,Computational modeling,Interpolation,Estimation
Kernel (linear algebra),Iterative reconstruction,Mathematical optimization,Tomographic reconstruction,Scalar (physics),Interpolation,Regularization (mathematics),Quantization (signal processing),Confidence interval,Mathematics
Journal
Volume
Issue
ISSN
38
6
1558-254X
Citations 
PageRank 
References 
0
0.34
0
Authors
4
Name
Order
Citations
PageRank
F Kucharczak100.34
F. Ben Bouallegue211.50
O. Strauss315321.17
Denis Mariano-Goulart463.92