Title
FELLA: an R package to enrich metabolomics data.
Abstract
The R package FELLA offers an innovative enrichment concept starting from a list of metabolites, based on a knowledge graph representation of the KEGG database that focuses on interpretability. Besides reporting a list of pathways, FELLA suggests intermediate entities that are of interest per se. Its usefulness has been shown at several molecular levels on six public datasets, including human and animal models. The user can run the enrichment analysis through a simple interactive graphical interface or programmatically. FELLA is publicly available in Bioconductor under the GPL-3 license.
Year
DOI
Venue
2018
10.1186/s12859-018-2487-5
BMC bioinformatics
Keywords
Field
DocType
Data mining,Knowledge representation,Metabolomics,Network analysis,Pathways
Knowledge graph,Knowledge representation and reasoning,Biology,Crosstalk,Bioconductor,Metabolomics,KEGG,Computational biology,Genetics,DNA microarray,R package
Journal
Volume
Issue
ISSN
19
1
1471-2105
Citations 
PageRank 
References 
0
0.34
8
Authors
5