Paper Info
Title
Towards the modeling of the Purkinje/myocardium coupled problem: A well-posedness analysis.
Abstract
The Purkinje network is the specialized conduction system in the heart. It ensures the physiological spread of the electrical wave in the ventricles. In this work, in an insulated heart framework, we model the free running Purkinje system, using the monodomain equation. The intra-myocardium part of the Purkinje fiber is coupled to the ventricular tissue using the bidomain equation. The coupling is performed through the extracellular potential. We discretize the problem in time using a semi-implicit scheme. Then, we write a variational formulation of the semi discrete problem in a non standard weighted Sobolev functional spaces. We prove the existence and uniqueness of the solution of the Purkinje/myocardium semi-discretized problem. We discretize in space by the finite element P1−Lagrange and conduct some numerical tests showing the anterograde and retrograde propagation of the electrical wave between the tissue and the Purkinje fibers.
Year
DOI
Venue
2019
10.1016/j.cam.2018.10.024
Journal of Computational and Applied Mathematics
Keywords
Field
DocType
92B05,35K55,35K57,65N38
Uniqueness,Discretization,Numerical tests,Coupling,Purkinje fibers,Mathematical analysis,Sobolev space,Finite element method,Mathematics,Electrical conduction system of the heart
Journal
Volume
ISSN
Citations 
351
0377-0427
0
PageRank 
References 
Authors
0.34
2
3
Name
Order
Citations
PageRank
Saloua Mani Aouadi172.49
W. Mbarki200.34
Nejib Zemzemi34212.17