Abstract | ||
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Highly personalised dietary advice based on combination of genetic information, such as Single Nucleotide Polymorphisms (SNPs) and 'nudge' theory is an emerging field of research towards a achieving a healthy lifestyle. The aim of this preliminary study is to explore possible links between leptin, a hormone which regulates energy balance on the body and DNA-based diet. A trial composed of 23 subjects was run to investigate whether nutrigenomic links exist for salivary leptin. The collected sample was analysed by ELISA, statistical methods and regression. This study compared leptin concentrations over 8 weeks of Intervention group and Control group, which follow and not follow DNA-based diet respectively. For the Intervention group, there was a trend of decreased leptin concentration, however without any statistical significance. Overall, correlation and statistical significance was found between salivary leptin and calorific intake. Moreover, regression models based on the data showed that leptin levels in saliva can be used to predict Body Mass Index (BMI) of subjects. |
Year | DOI | Venue |
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2018 | 10.1109/BIOCAS.2018.8584802 | 2018 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS): ADVANCED SYSTEMS FOR ENHANCING HUMAN HEALTH |
Keywords | Field | DocType |
Personalised Diet,Nudge Theory,Leptin,Nutrigenomics,Saliva diagnostics | Regression analysis,Computer science,Artificial intelligence,Hormone,Computer vision,Leptin,Internal medicine,Body mass index,DNA,Single-nucleotide polymorphism,Statistical significance,Saliva,Endocrinology | Conference |
ISSN | Citations | PageRank |
2163-4025 | 0 | 0.34 |
References | Authors | |
0 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Francesca R. Cavallo | 1 | 0 | 0.34 |
Khalid B. Mirza | 2 | 0 | 2.70 |
Christofer Toumazou | 3 | 265 | 59.06 |