Title
Cross-Environment Comparison of a Bioinformatics Pipeline - Perspectives for Hybrid Computations.
Abstract
In this work a previously published bioinformatics pipeline was reimplemented across various computational platforms, and the performances of its steps evaluated. The tested environments were: (I) dedicated bioinformatics-specific server (II) low-power single node (III) HPC single node (IV) virtual machine. The pipeline was tested on a use case of the analysis of a single patient to assess single-use performances, using the same configuration of the pipeline to be able to perform meaningful comparison and search the optimal environment/hybrid system configuration for biomedical analysis. Performances were evaluated in terms of execution wall time, memory usage and energy consumption per patient. Our results show that, albeit slower, low power single nodes are comparable with other environments for most of the steps, but with an energy consumption two to four times lower. These results indicate that these environments are viable candidates for bioinformatics clusters where long term efficiency is a factor.
Year
DOI
Venue
2018
10.1007/978-3-030-10549-5_50
Lecture Notes in Computer Science
Keywords
Field
DocType
Whole genome sequencing,Bioinformatic pipeline,Low-power,GATK-LODn pipeline
Cluster (physics),Virtual machine,Computer science,Parallel computing,Bioinformatics,Energy consumption,Hybrid system,Computation
Conference
Volume
ISSN
Citations 
11339
0302-9743
0
PageRank 
References 
Authors
0.34
2
9