Title
The Optimization of Combination Chemotherapy Schedules in the Presence of Drug Resistance.
Abstract
This paper aims to devise efficient combination chemotherapy schedules that determine the dosages of drugs administered to cancer patients with drug resistance that, as a Gordian knot to cancer chemotherapy, may weaken the efficacy of chemotherapy. To characterize cell growth, we use the existing cell cycle-specific model, in which the mechanism of acquired drug resistance is incorporated. Subsequ...
Year
DOI
Venue
2019
10.1109/TASE.2018.2873668
IEEE Transactions on Automation Science and Engineering
Keywords
Field
DocType
Drugs,Chemotherapy,Resistance,Tumors,Optimization,Schedules,Cancer
Memetic algorithm,Mathematical optimization,Heuristic,Dose,Drug resistance,Computer science,Schedule,Local search (optimization),Optimization problem,Drug
Journal
Volume
Issue
ISSN
16
1
1545-5955
Citations 
PageRank 
References 
0
0.34
0
Authors
5
Name
Order
Citations
PageRank
Peilian Wang100.68
Ran Liu2417.64
Z. B. Jiang324236.08
Yang Yao400.34
Zan Shen510.69