Title | ||
---|---|---|
The Optimization of Combination Chemotherapy Schedules in the Presence of Drug Resistance. |
Abstract | ||
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This paper aims to devise efficient combination chemotherapy schedules that determine the dosages of drugs administered to cancer patients with drug resistance that, as a Gordian knot to cancer chemotherapy, may weaken the efficacy of chemotherapy. To characterize cell growth, we use the existing cell cycle-specific model, in which the mechanism of acquired drug resistance is incorporated. Subsequ... |
Year | DOI | Venue |
---|---|---|
2019 | 10.1109/TASE.2018.2873668 | IEEE Transactions on Automation Science and Engineering |
Keywords | Field | DocType |
Drugs,Chemotherapy,Resistance,Tumors,Optimization,Schedules,Cancer | Memetic algorithm,Mathematical optimization,Heuristic,Dose,Drug resistance,Computer science,Schedule,Local search (optimization),Optimization problem,Drug | Journal |
Volume | Issue | ISSN |
16 | 1 | 1545-5955 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Peilian Wang | 1 | 0 | 0.68 |
Ran Liu | 2 | 41 | 7.64 |
Z. B. Jiang | 3 | 242 | 36.08 |
Yang Yao | 4 | 0 | 0.34 |
Zan Shen | 5 | 1 | 0.69 |