Title
Sliding window correlation analysis: Modulating window shape for dynamic brain connectivity in resting state.
Abstract
The sliding window correlation (SWC) analysis is a straightforward and common approach for evaluating dynamic functional connectivity. Despite the fact that sliding window analyses have been long used, there are still considerable technical issues associated with the approach. A great effort has recently been dedicated to investigate the window setting effects on dynamic connectivity estimation. In this direction, tapered windows have been proposed to alleviate the effect of sudden changes associated with the edges of rectangular windows. Nevertheless, the majority of the windows exploited to estimate brain connectivity tend to suppress dynamic correlations, especially those with faster variations over time. Here, we introduced a window named modulated rectangular (mRect) to address the suppressing effect associated with the conventional windows. We provided a frequency domain analysis using simulated time series to investigate how sliding window analysis (using the regular window functions, e.g. rectangular and tapered windows) may lead to unwanted spectral modulations, and then we showed how this issue can be alleviated through the mRect window. Moreover, we created simulated dynamic network data with altering states over time using simulated fMRI time series, to examine the performance of different windows in tracking network states. We quantified the state identification rate of different window functions through the Jaccard index, and observed superior performance of the mRect window compared to the conventional window functions. Overall, the proposed window function provides an approach that improves SWC estimations, and thus the subsequent inferences and interpretations based on the connectivity network analyses.
Year
DOI
Venue
2019
10.1016/j.neuroimage.2019.02.001
NeuroImage
Keywords
Field
DocType
Sliding window correlation analysis,Dynamic brain connectivity,Resting state,Modulated rectangular window,Connectivity network states,Network states transition
Dynamic network analysis,Frequency domain,Sliding window protocol,Resting state fMRI,Cognitive psychology,Algorithm,Psychology,Jaccard index,Dynamic functional connectivity,Window function,Modulation (music)
Journal
Volume
ISSN
Citations 
189
1053-8119
4
PageRank 
References 
Authors
0.40
25
5
Name
Order
Citations
PageRank
Fatemeh Mokhtari151.09
Milad I Akhlaghi240.40
Sean L. Simpson3916.16
Guorong Wu472162.83
Paul J. Laurienti526321.70