Title
The individual functional connectome is unique and stable over months to years.
Abstract
Functional connectomes computed from fMRI provide a means to characterize individual differences in the patterns of BOLD synchronization across regions of the entire brain. Using four resting-state fMRI datasets with a wide range of ages, we show that individual differences of the functional connectome are stable across 3 months to 1–2 years (and even detectable at above-chance levels across 3 years). Medial frontal and frontoparietal networks appear to be both unique and stable, resulting in high ID rates, as did a combination of these two networks. We conduct analyses demonstrating that these results are not driven by head motion. We also show that edges contributing the most to a successful ID tend to connect nodes in the frontal and parietal cortices, while edges contributing the least tend to connect cross-hemispheric homologs. Our results demonstrate that the functional connectome is stable across years and that high ID rates are not an idiosyncratic aspect of a specific dataset, but rather reflect stable individual differences in the functional connectivity of the brain.
Year
DOI
Venue
2019
10.1016/j.neuroimage.2019.02.002
NeuroImage
Field
DocType
Volume
Neuroscience,Biology,Connectome,Entire brain,Genetics
Journal
189
ISSN
Citations 
PageRank 
1053-8119
6
0.49
References 
Authors
14
4
Name
Order
Citations
PageRank
Corey Horien1231.54
Xilin Shen227814.18
Dustin Scheinost328722.17
R Todd Constable484877.34