Title
Improving Sepsis Treatment Strategies by Combining Deep and Kernel-Based Reinforcement Learning.
Abstract
Sepsis is the leading cause of mortality in the ICU. It is challenging to manage because individual patients respond differently to treatment. Thus, tailoring treatment to the individual patient is essential for the best outcomes. In this paper, we take steps toward this goal by applying a mixture-of-experts framework to personalize sepsis treatment. The mixture model selectively alternates between neighbor-based (kernel) and deep reinforcement learning (DRL) experts depending on patient's current history. On a large retrospective cohort, this mixture-based approach outperforms physician, kernel only, and DRL-only experts.
Year
Venue
DocType
2018
AMIA
Conference
Volume
ISSN
Citations 
abs/1901.04670
1942-597X
0
PageRank 
References 
Authors
0.34
4
9
Name
Order
Citations
PageRank
Xuefeng Peng100.68
Yi Ding210037.68
David Wihl300.68
Gottesman, Omer413.06
Matthieu Komorowski5174.74
Li-wei H Lehman619218.54
Andrew Slavin Ross7665.03
Aldo Faisal800.34
finale doshivelez957451.99