Title
CPR Guideline Chest Compression Depths May Exceed Requirements for Optimal Physiological Response
Abstract
A twelve-animal porcine study dataset was retrospectively analyzed to assess associations between chest compression (CC) depth, systolic blood pressure (SBP) and end-tidal carbon dioxide (EtCO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ). Manual CCs were applied for 7 two-minute episodes, at CC depths between 10mm-55mm. A rolling 15s analysis window was applied to the continuous signals. Mean peak values were calculated for each window. Correlation analysis was applied to assess strength of association. Optimal CC depth to achieve physiological targets was determined via cut-off analysis. A total of 672 observations for each variable were available for analysis. Pearson correlations (95% confidence interval; p-value) between CC depth and both SBP and ETCO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> were 0.84 and 0.75 respectively. Optimal CC depth cutoff (sensitivity, specificity) to achieve SBP ≥ 100mmHg and EtCO2 ≥ 10mmHg was 33 mm (98.29%, 88.94%)and 20 mm (95.08%, 78.30%) respectively. A reasonable relationship between CC depth and physiological response was observed. Optimal SBP and EtCO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> cut-offs were achieved significantly below guideline depths. Furthermore, cut-off analysis suggests a disparity between CC depth and physiological targets.
Year
DOI
Venue
2018
10.22489/CinC.2018.116
2018 Computing in Cardiology Conference (CinC)
Keywords
Field
DocType
optimal SBP,guideline depths,physiological targets,CPR guideline chest compression depths,optimal physiological response,twelve-animal porcine study dataset,chest compression depth,systolic blood pressure,end-tidal carbon dioxide,analysis window,mean peak values,correlation analysis,cut-off analysis,optimal CC depth cutoff
Compression (physics),Internal medicine,Cutoff,Cardiology,Blood pressure,Guideline,Confidence interval,Mathematics,Correlation analysis
Conference
Volume
ISSN
ISBN
45
2325-8861
978-1-7281-0924-4
Citations 
PageRank 
References 
0
0.34
0
Authors
9
Name
Order
Citations
PageRank
Olibhéar McAlister100.34
Daniel Gueldenring2106.55
Dewar D. Finlay38722.60
RR Bond46830.02
Hannah Torney500.34
Ben McCartney600.34
Laura Davis711.30
Paul Crawford800.68
Adam Harvey900.34