Paper Info
Title
A Multiscale Intracranial Pressure Signal Simulator
Abstract
Intracranial pressure (ICP) is a key vital sign whose temporal behavior across multiple time scales is increasingly being studied, e.g., to assess brain compliance or to estimate cerebral perfusion. In this paper we present a multiscale ICP signal simulator that acts on three time scales: Long-term ICP trends (minutes to hours), respiration-induced changes in ICP and single ICP pulses. The long-term trends are based on a mechanistic ICP model, whereas the respiration-induced and intrabeat changes are represented through phenomenological models. The latter capture waveform properties extracted from real patients in our ICP database as well as waveform features described in the literature. Potential use cases of the simulator include the evaluation of ICP signal analysis algorithms and testing of patient-monitor alarm settings.
Year
DOI
Venue
2018
10.22489/CinC.2018.010
2018 Computing in Cardiology Conference (CinC)
Keywords
Field
DocType
intrabeat changes,phenomenological models,capture waveform properties,ICP database,ICP signal analysis algorithms,multiscale intracranial pressure signal simulator,multiple time scales,brain compliance,cerebral perfusion,multiscale ICP signal simulator,single ICP pulses,long-term trends,mechanistic ICP model,long-term ICP trends,key vital sign,temporal behavior,waveform feature extraction,respiration-induced changes
Signal processing,Computer science,Simulation,Waveform,Intracranial pressure,Cerebral perfusion pressure
Conference
Volume
ISSN
ISBN
45
2325-8861
978-1-7281-0924-4
Citations 
PageRank 
References 
0
0.34
2
Authors
4
Name
Order
Citations
PageRank
Federico Wadehn100.34
David J. Mack220.73
Emanuela Keller364.39
Thomas Heldt429.54