Title
Pulsed Excitation in Magnetic Particle Imaging.
Abstract
Magnetic Particle Imaging (MPI) is a promising new tracer-based imaging modality. The steady-state, nonlinear magnetization physics most fundamental to MPI typically predicts improving resolution with increasing tracer magnetic core size. For larger tracers, and given typical excitation slew rates, this steady-state prediction is compromised by dynamic processes that induce a significant secondary blur and prevent us from achieving high resolution using larger tracers. Here we propose a new method of excitation and signal encoding in MPI we call pulsed MPI to overcome this phenomenon. Pulsed MPI allows us to directly encode the steady-state magnetic physics into the time-domain signal. This in turn gives rise to a simple reconstruction algorithm to obtain images free of secondary relaxation-induced blur. Here we provide a detailed description of our approach in 1D, discuss how it compares with alternative approaches, and show experimental data demonstrating better than 500 μm resolution (at 7 T/m) with large tracers. Finally we show experimental images from a 2D implementation.
Year
DOI
Venue
2019
10.1109/TMI.2019.2898202
IEEE transactions on medical imaging
Keywords
Field
DocType
Magnetic resonance imaging,Steady-state,Magnetic cores,Image resolution,Magnetic domains,Signal resolution
Magnetic particle imaging,Computer vision,Computational physics,Nonlinear system,Magnetization,Excitation,Reconstruction algorithm,Magnetic core,Artificial intelligence,Image resolution,Magnetic domain,Mathematics
Journal
Volume
Issue
ISSN
38
10
1558-254X
Citations 
PageRank 
References 
2
0.47
0
Authors
7
Name
Order
Citations
PageRank
Zhi Wei Tay120.81
Daniel Hensley221.14
Jie Ma320.47
Prashant Chandrasekharan420.81
bo zheng5257.29
Patrick W. Goodwill67510.14
Steven Conolly720.47