Title
HMNPPID: A Database of Protein-protein Interactions Associated with Human Malignant Neoplasms
Abstract
Protein-protein interactions (PPIs) play a key role in varies aspects of the structural and functional organization of the cell. Knowledge about them unveils the molecular mechanisms of biological processes. At the same time, the PPIs related to human malignant neoplasms can shed light on the biology behind these neoplasms. However, there is no such PPI database available so far. We constructed a database of protein-protein interactions associated with human malignant neoplasms, named HMNPPID, which contains the PPIs of 171 kinds of human malignant neoplasms. HMNPPID provides healthcare professionals with the PPIs of specific malignant neoplasm without digging into amounts of biomedical literatures, which significantly improves the efficiency of researches on the PPIs of malignant neoplasms. In addition, a visualization program, VisualPPI, is provided to facilitate the analysis of the specific PPI network for a malignant neoplasm.
Year
DOI
Venue
2018
10.1109/BIBM.2018.8621402
2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Keywords
Field
DocType
Protein-protein Interactions,Human Malignant Neoplasms
Protein–protein interaction,Computer science,Bioinformatics,Database
Conference
ISSN
ISBN
Citations 
2156-1125
978-1-5386-5489-7
0
PageRank 
References 
Authors
0.34
0
10
Name
Order
Citations
PageRank
Qingqing Li1908.58
Zhihao Yang27315.35
Zhehuan Zhao302.70
Ling Luo4393.47
Zhiheng Li5226.42
Lei Wang65613.90
Yin Zhang771.77
Hongfei Lin8768122.52
Jian Wang900.68
Yijia Zhang1045.47