Title
Changes in BOLD and ADC weighted imaging in acute hypoxia during sea-level and altitude adapted states.
Abstract
Acute normobaric hypoxia as well as longstanding hypobaric hypoxia induce pronounced physiological changes and may eventually lead to impairment of cerebral function. The aim of the present study is to investigate the effect of hypoxia on the cerebral activation response as well as to explore possible structural changes as measured by diffusion weighted imaging. Eleven healthy sea-level residents were studied after 5 weeks of adaptation to high altitude conditions at Chacaltaya, Bolivia (5260 m). The subjects were studied immediately after return to sea-level in hypoxic and normoxic conditions, and the examinations repeated 6 months later after re-adaptation to sea-level conditions.
Year
DOI
Venue
2005
10.1016/j.neuroimage.2005.06.032
NeuroImage
Keywords
Field
DocType
BOLD,CBF,CMRO2,DPG,fMRI,MRI,PET,ROI
Effective diffusion coefficient,Diffusion MRI,Sea level,Acclimatization,Hypoxia (medical),Pathology,Developmental psychology,Effects of high altitude on humans,Internal medicine,Cardiology,Psychology,Altitude,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
28
4
1053-8119
Citations 
PageRank 
References 
3
0.49
0
Authors
5
Name
Order
Citations
PageRank
E ROSTRUP114617.99
Henrik B W Larsson230.49
Alfred P Born330.49
Gitte M. Knudsen48917.15
Olaf B Paulson524528.25