Title
Discovering the Type 2 Diabetes in Electronic Health Records using the Sparse Balanced Support Vector Machine.
Abstract
The diagnosis of type 2 diabetes (T2D) at an early stage has a key role for an adequate T2D integrated management system and patient's follow-up. Recent years have witnessed an increasing amount of available electronic health record (EHR) data and machine learning (ML) techniques have been considerably evolving. However, managing and modeling this amount of information may lead to several challenges, such as overfitting, model interpretability, and computational cost. Starting from these motivations, we introduced an ML method called sparse balanced support vector machine (SB-SVM) for discovering T2D in a novel collected EHR dataset (named Federazione Italiana Medici di Medicina Generale dataset). In particular, among all the EHR features related to exemptions, examination, and drug prescriptions, we have selected only those collected before T2D diagnosis from an uniform age group of subjects. We demonstrated the reliability of the introduced approach with respect to other ML and deep learning approaches widely employed in the state-of-the-art for solving this task. Results evidence that the SB-SVM overcomes the other state-of-the-art competitors providing the best compromise between predictive performance and computation time. Additionally, the induced sparsity allows to increase the model interpretability, while implicitly managing high-dimensional data and the usual unbalanced class distribution.
Year
DOI
Venue
2020
10.1109/JBHI.2019.2899218
IEEE journal of biomedical and health informatics
Keywords
Field
DocType
Diabetes,Support vector machines,Feature extraction,Computational modeling,Data models,Decision support systems,Informatics
Interpretability,Clustering high-dimensional data,Pattern recognition,Computer science,Support vector machine,Integrated management system,Artificial intelligence,Overfitting,Deep learning,Machine learning,Computation
Journal
Volume
Issue
ISSN
24
1
2168-2194
Citations 
PageRank 
References 
1
0.35
0
Authors
4
Name
Order
Citations
PageRank
Michele Bernardini123.07
luca romeo2219.59
Paolo Misericordia310.35
Emanuele Frontoni424847.04