Title
3DBIONOTES v3.0: Crossing molecular and structural biology data with genomic variations.
Abstract
Motivation: Many diseases are associated to single nucleotide polymorphisms that affect critical regions of proteins as binding sites or post translational modifications. Therefore, analysing genomic variants with structural and molecular biology data is a powerful framework in order to elucidate the potential causes of such diseases. Results: A new version of our web framework 3DBIONOTES is presented. This version offers new tools to analyse and visualize protein annotations and genomic variants, including a contingency analysis of variants and amino acid features by means of a Fisher exact test, the integration of a gene annotation viewer to highlight protein features on gene sequences and a protein-protein interaction viewer to display protein annotations at network level.
Year
DOI
Venue
2019
10.1093/bioinformatics/btz118
BIOINFORMATICS
Field
DocType
Volume
Data mining,Structural biology,Computer science,Computational biology
Journal
35
Issue
ISSN
Citations 
18
1367-4803
0
PageRank 
References 
Authors
0.34
1
4
Name
Order
Citations
PageRank
Joan Segura1152.50
Ruben Sanchez-Garcia251.50
C. O. S. Sorzano35011.68
José María Carazo465456.25