Title | ||
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Feedback control of impaired cerebral autoregulation in preterm infants: Mathematical modelling |
Abstract | ||
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Impaired cerebral autoregulation is often the cause of cerebral hemorrhage in preterm infants. The place of cerebral bleeding is most frequently the germinal matrix being a highly vascularized layer of neuronal and glial precursors. A passive, linear, dependency of the cerebral blood flow on the arterial mean pressure leads to damage of fragile blood vessels of the germinal matrix. A mathematical model of impaired cerebral autoregulation is proposed. Feedback controls, which are able to compensate fails of autoregulation, are constructed and their robustness against all unpredictable admissible disturbances is proven using techniques of viability theory. |
Year | DOI | Venue |
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2017 | 10.1109/MED.2017.7984123 | 2017 25th Mediterranean Conference on Control and Automation (MED) |
Keywords | Field | DocType |
feedback control,impaired cerebral autoregulation,preterm infants,mathematical modelling,cerebral hemorrhage,cerebral bleeding,germinal matrix,vascularized layer,neuronal precursors,glial precursors,cerebral blood flow,arterial mean pressure,fragile blood vessels,robustness,admissible disturbances,viability theory | Germinal matrix,Autoregulation,Computer science,Internal medicine,Control theory,Viability theory,Cardiology,Cerebral Bleeding,Cerebral autoregulation,Arterial mean pressure,Blood pressure,Cerebral blood flow | Conference |
ISSN | ISBN | Citations |
2325-369X | 978-1-5090-4534-1 | 0 |
PageRank | References | Authors |
0.34 | 3 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Nikolai D. Botkin | 1 | 21 | 9.26 |
Varvara L. Turova | 2 | 21 | 9.05 |
Renée Lampe | 3 | 0 | 2.37 |