Title
Preliminary study of visualizing membrane structures of spiculated pulmonary nodules in three-dimensional thoracic CT images
Abstract
Research results from the National Lung Screening Trial revealed that screening for lung cancer with low-dose CT (LDCT) reduces lung cancer mortality in heavy smokers by 20% compared to radiography. While this study does show the efficacy of CT-based screening, radiologists often face the problem of estimating the malignant likelihoods of pulmonary nodules detected on LDCT screening for maximizing patient survival and for preserving lung function. Spiculation is considered as one of the indicators of nodule malignancy and an important feature to assess requirements on a patient-tailored follow-up procedure. However, the spiculation is also observed in some benign nodules, particularly in tuberculoma. The elucidation of the spliculation morphology in 3D thoracic CT images is an important preliminary step towards developing the malignant discrimination strategies from benign nodules. In this study, we present a visualization method to reveal a spatial configuration of spiculation of pulmonary nodules in three-dimensional thoracic CT images. Applying the method to an example of malignant nodule with the spiculated margins, the visualizing preliminary result of the spatial configuration reveals the presence of membrane structures of spiculation.
Year
DOI
Venue
2016
10.1117/12.2216691
Proceedings of SPIE
Keywords
Field
DocType
pulmonary nodule,speculation,membrane structure,3D thoracic CT
Lung cancer,Lung,Spatial configuration,Malignancy,Artificial intelligence,Radiography,National Lung Screening Trial,Computer vision,Medical physics,Radiology,Tuberculoma,Cancer,Physics
Conference
Volume
ISSN
Citations 
9788
0277-786X
0
PageRank 
References 
Authors
0.34
0
8
Name
Order
Citations
PageRank
Yoshiki Kawata119254.44
Noboru Niki218866.10
Hironobu Ohmatsu313845.23
keiju aokage401.35
masahiko kusumoto54616.28
takaaki tsuchida604.39
Kenji Eguchi711.76
Masahiro Kaneko85519.24