Title
Glucose sensing electrode system based on polymeric microneedles
Abstract
Microneedles are largely applied in biomedicine, both in diagnostics and therapeutics, since they can be considered the perfect interface between patient and sensing/dispensing devices. In this paper, we present an electro-chemical biosensor based on polymeric microneedles array for the measure of glucose level in interstitial fluids. The microneedles array has been fabricated by photolithography of a polymer, PolyEthylene Glycol DiAcrylate hydrogel, mixed with an enzyme, Glucose oxidase, and a redox mediator, the Vynilferrocene. The microneedles array acts as a working electrode when gold plated by sputtering and their tips have been etched to create a sensitive area. The redox reaction with glucose creates a charge transfer, enhanced by the redox mediator, resulting in a current proportional to the glucose concentration.
Year
DOI
Venue
2016
10.1109/SAS.2016.7479821
2016 IEEE Sensors Applications Symposium (SAS)
Keywords
Field
DocType
Microneedles,glucose sensor,microfabrication
Nanotechnology,Polymer,Glucose oxidase,Computer science,Photolithography,Real-time computing,Polyethylene glycol,Biosensor,Working electrode,Electrode,Redox
Conference
Citations 
PageRank 
References 
0
0.34
0
Authors
6
Name
Order
Citations
PageRank
Principia Dardano101.01
A. Caliò200.68
V. Di Palma301.01
Michele Bevilacqua400.34
A. Di Matteo500.68
L. De Stefano600.68