Abstract | ||
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Microneedles are largely applied in biomedicine, both in diagnostics and therapeutics, since they can be considered the perfect interface between patient and sensing/dispensing devices. In this paper, we present an electro-chemical biosensor based on polymeric microneedles array for the measure of glucose level in interstitial fluids. The microneedles array has been fabricated by photolithography of a polymer, PolyEthylene Glycol DiAcrylate hydrogel, mixed with an enzyme, Glucose oxidase, and a redox mediator, the Vynilferrocene. The microneedles array acts as a working electrode when gold plated by sputtering and their tips have been etched to create a sensitive area. The redox reaction with glucose creates a charge transfer, enhanced by the redox mediator, resulting in a current proportional to the glucose concentration. |
Year | DOI | Venue |
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2016 | 10.1109/SAS.2016.7479821 | 2016 IEEE Sensors Applications Symposium (SAS) |
Keywords | Field | DocType |
Microneedles,glucose sensor,microfabrication | Nanotechnology,Polymer,Glucose oxidase,Computer science,Photolithography,Real-time computing,Polyethylene glycol,Biosensor,Working electrode,Electrode,Redox | Conference |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
6 |
Name | Order | Citations | PageRank |
---|---|---|---|
Principia Dardano | 1 | 0 | 1.01 |
A. Caliò | 2 | 0 | 0.68 |
V. Di Palma | 3 | 0 | 1.01 |
Michele Bevilacqua | 4 | 0 | 0.34 |
A. Di Matteo | 5 | 0 | 0.68 |
L. De Stefano | 6 | 0 | 0.68 |