Title | ||
---|---|---|
Capillary number effect on the depletion of leucocytes of blood in microfiltration chips for the isolation of circulating tumor cells |
Abstract | ||
---|---|---|
To increase the purity of isolated circulating tumor cells (CTCs) in microfiltration chips, the depletion of leucocytes in human blood was systematically studied as a function of two dimensionless parameters, Capillary number Ca and the normalized leucocyte diameter. An optimized Ca* of 0.038 was identified to differentiate the capturing of cancer cells and leucocytes. Such Ca effect can be applied as a guideline for designing an optimized microfiltration system with both high capture efficiency and purity for isolating CTCs from human blood. |
Year | DOI | Venue |
---|---|---|
2016 | 10.1109/NEMS.2016.7758264 | 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) |
Keywords | DocType | ISSN |
circulating tumor cells,CTCs,Capillary number,leucocyte depletion,microfiltration | Conference | 2474-3747 |
ISBN | Citations | PageRank |
978-1-5090-1948-9 | 0 | 0.34 |
References | Authors | |
0 | 10 |
Name | Order | Citations | PageRank |
---|---|---|---|
Cong Zhao | 1 | 0 | 0.68 |
Kui Song | 2 | 0 | 0.68 |
Jeng Hun Lee | 3 | 0 | 0.34 |
Shin Young Jeong | 4 | 0 | 0.34 |
Lixie Hu | 5 | 0 | 0.34 |
Xingsu Yu | 6 | 0 | 0.34 |
Huifang Su | 7 | 0 | 0.34 |
Zhenfeng Zhang | 8 | 0 | 0.34 |
Yitshak Zohar | 9 | 0 | 1.01 |
Yi-Kuen Lee | 10 | 7 | 11.16 |