Name
Title | ||
|---|---|---|
Local inhibition of microstimulation-induced neural excitations by near-infrared laser irradiation in mouse cerebral slices in vitro |
Abstract | ||
|---|---|---|
Electrical microstimulation and near-infrared (NIR) laser light irradiation were combined to control neural activities in cerebral cortex in vitro. Spatio-temporal patterns of suprathreshold neural excitations in the primary visual cortex of mouse cerebral slices were visualized by the Ca
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-sensitive dye imaging. In response to a single pulse of the biphasic stimulus current delivered to the layer IV, neural excitations were initiated around the stimulating electrode tip, and then synaptically propagated to the layer II/III. The neural excitations and population excitatory post-synaptic potential in the layer II/III were inhibited in a spot region where NIR laser light was illuminated. This inhibitory effect was larger when the carbon-nanotube-bundle fiber as a light absorber was placed within the spot region. The present results suggested that the NIR laser light can be used to locally inhibit trans-synaptic neural excitations induced by electrical microstimulations. |
Year | DOI | Venue |
|---|---|---|
2017 | 10.1109/NER.2017.8008339 | 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER) |
Keywords | Field | DocType |
microstimulation-induced neural excitation,in vitro mouse cerebral slices,electrical microstimulation,near-infrared,NIR laser light irradiation,neural activity,in vitro cerebral cortex,suprathreshold neural excitation,primary visual cortex,calcium ion-sensitive dye imaging,biphasic stimulus current,electrode tip,post-synaptic potential,inhibitory effect,carbon-nanotube-bundle fiber,light absorber,transsynaptic neural excitation | Population,Computer science,Inhibitory postsynaptic potential,Artificial intelligence,Cerebral cortex,Computer vision,Visual cortex,Biophysics,Microstimulation,Excitatory postsynaptic potential,Laser,Optoelectronics,Fiber laser | Conference |
ISSN | ISBN | Citations |
1948-3546 | 978-1-5090-4604-1 | 0 |
PageRank | References | Authors |
0.34 | 3 | 5 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Yuki Hayashida | 1 | 16 | 7.10 |
| Yuya Sakata | 2 | 0 | 0.34 |
| Yuta Tanaka | 3 | 0 | 1.35 |
| Tomohiro Nomoto | 4 | 0 | 0.68 |
| Tetsuya Yagi | 5 | 140 | 27.73 |