Title
Automated brain extraction and immersive exploration of its layers in virtual reality for the rhesus macaque MRI data sets
Abstract
As we know, the rhesus macaque as a nonhuman primate is quite similar to a human being in genetics. Moreover, it has become essential in animal model anatomy and physiology in many modern medicine research such as the cardiovascular and cerebrovascular diseases in the recent years. This paper describes a pipeline from the raw rhesus macaque brain magnetic resonance imaging data to intuitive 3D inspection of its layers. Brain extraction is an initial step for subsequent analyses, but most of the existing methods so far are designed for human brain, which does not work well with the rhesus macaque. Firstly, we propose a reliable and efficient method to extract the brain from magnetic resonance imaging data sets based on dividing the brain into blocks. Then, we design a trapezoid opacity transfer function based on Compute Unified Device Architecture (CUDA)-based real-time volume ray casting, which is dedicated to volume rendering to make the inspection more intuitive. Besides, for an immersive exploration in virtual reality benefits understanding the volumetric data sets, so we also design a layer filter for the segmented rhesus macaque brain data sets, which facilitates the inspection of the interior in Region of Interest (ROI) by an intuitive bimanual interaction via a Leap Motion sensor. Our experiments prove usability and efficiency.
Year
DOI
Venue
2019
10.1002/cav.1841
COMPUTER ANIMATION AND VIRTUAL WORLDS
Keywords
Field
DocType
bimanual gesture interaction,brain extraction,rhesus macaque,volume visualization,3D inspection
Computer vision,Data set,Virtual reality,Volume visualization,Computer graphics (images),Computer science,Rhesus macaque,Immersion (virtual reality),Artificial intelligence
Journal
Volume
Issue
ISSN
30.0
1
1546-4261
Citations 
PageRank 
References 
0
0.34
19
Authors
7
Name
Order
Citations
PageRank
Yanlin Luo100.34
Bin Gao2636.51
Yiyi Deng301.35
Xiaoming Zhu400.34
T. Jiang51419128.59
Xudong Zhao600.34
Zhengyi Yang701.01