Title
Hand-held photoacoustic imager for theranostics in 3D.
Abstract
A handheld approach to three-dimensional (3D) photoacoustic imaging is essential in clinical applications. To this end, we develop a 3D handheld photoacoustic imager for dynamic (temporally and spatially) volumetric visualization. In this 3D imager, the optically transmitting part and the acoustically receiving part are integrated into a single handheld probe with a compact size about 160 mm×64 mm×40 mm. Besides, a dedicated imaging reconstruction algorithm for the heterogeneous medium is developed based on the phase-shift migration (PSM) method in frequency domain, which deals well with the stratified condition in the designed system. Dynamic 3D imaging supporting flexible handheld operation is demonstrated with needle biopsy and in-vitro temperature measurement for photothermal therapy. The development of such a 3D handheld photoacoustic system paves the way for compact and handheld-operating implementations, and its further clinical exploration is promising.
Year
DOI
Venue
2019
10.1109/TMI.2019.2900656
IEEE transactions on medical imaging
Keywords
Field
DocType
Three-dimensional displays,Optical imaging,Biomedical optical imaging,Acoustics,Acoustic arrays,Optical sensors
Frequency domain,Computer vision,Photoacoustic imaging in biomedicine,Photothermal therapy,Visualization,Optics,Mobile device,Reconstruction algorithm,Artificial intelligence,Optical imaging,Mathematics
Journal
Volume
Issue
ISSN
38
9
1558-254X
Citations 
PageRank 
References 
0
0.34
0
Authors
8
Name
Order
Citations
PageRank
Siyu Liu1188.31
Xiaohua Feng202.03
Haoran Jin333.86
Ruochong Zhang413.77
Yunqi Luo521.10
Zesheng Zheng633.15
Fei Gao7710.00
Yuanjin Zheng832872.86