Title
Platform and algorithm effects on computational fluid dynamics applications in life sciences.
Abstract
High Performance Computing (HPC) is a mainstream mode of exploration and analysis in different fields, not only technical but also social and life sciences. A well-established HPC domain is medicine, and cardiovascular sciences in particular. The adoption of CFD as a tool for diagnosis, prognosis, and treatment planning in the clinical routine is however still an open challenge. This computational tool, required by Computer Aided Clinical Trials and Surgical Planning, calls for significant computational resources to face both large volume of patients and diverse timelines ranging from election to emergency scenarios. Traditional local clusters may be not adequate to deliver the computational needs. Alternative solutions like grids and on-demand cloud resources need to be seriously considered. This paper proposes methodologies and protocols to identify the optimal choice of computing platforms for hemodynamics computations that will be increasingly needed in the future and the optimal scheduling of the tasks across the selected resources. We focus on hemodynamics in patient-specific settings and present extensive results on different platforms. We propose a way to measure and estimate performance and running time under realistic scenarios tailored to the utility function of the simulation. We discuss in detail the optimal (parallel) partitioning of the domain of a problem of interest with different mathematical approaches. We show that an overlapping splitting is generally advantageous and the detection of optimal overlapping has the potential to significantly reduce computational costs of the entire solution process and the communication volume across the platforms.
Year
DOI
Venue
2017
10.1016/j.future.2016.03.024
Future Generation Computer Systems
Keywords
Field
DocType
Applied computing in medicine,Platform heterogeneity,Cloud computing,Computational fluid dynamics,Parallel overlapping domain decomposition,Performance analysis
Supercomputer,Computer science,Computer-aided,Scheduling (computing),Timeline,Ranging,Computational fluid dynamics,Cloud computing,Computation,Distributed computing
Journal
Volume
ISSN
Citations 
67
0167-739X
2
PageRank 
References 
Authors
0.38
17
6
Name
Order
Citations
PageRank
Sofia Guzzetti120.38
Tiziano Passerini2184.14
Jaroslaw Slawinski3357.50
Umberto Villa4306.64
Alessandro Veneziani513121.79
Vaidy Sunderam61268237.47