Title
Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson's Disease.
Abstract
A self-managed, home-based system for the automated assessment of a selected set of Parkinson's disease motor symptoms is presented. The system makes use of an optical RGB-Depth device both to implement its gesture-based human computer interface and for the characterization and the evaluation of posture and motor tasks, which are specified according to the Unified Parkinson's Disease Rating Scale (UPDRS). Posture, lower limb movements and postural instability are characterized by kinematic parameters of the patient movement. During an experimental campaign, the performances of patients affected by Parkinson's disease were simultaneously scored by neurologists and analyzed by the system. The sets of parameters which best correlated with the UPDRS scores of subjects' performances were then used to train supervised classifiers for the automated assessment of new instances of the tasks. Results on the system usability and the assessment accuracy, as compared to clinical evaluations, indicate that the system is feasible for an objective and automated assessment of Parkinson's disease at home, and it could be the basis for the development of neuromonitoring and neurorehabilitation applications in a telemedicine framework.
Year
DOI
Venue
2019
10.3390/s19051129
SENSORS
Keywords
Field
DocType
Parkinson's disease,UPDRS tasks,movement disorders,posture,postural stability,center of mass,RGB-depth,automated assessment,machine learning,at-home monitoring,neurorehabilitation
Telemedicine,Parkinson's disease,Movement disorders,Kinematics,Gesture,Usability,Electronic engineering,Rating scale,Physical medicine and rehabilitation,Neurorehabilitation,Engineering
Journal
Volume
Issue
ISSN
19
5
1424-8220
Citations 
PageRank 
References 
1
0.36
0
Authors
9
Name
Order
Citations
PageRank
Claudia Ferraris183.01
Roberto Nerino2114.12
A. Chimienti311621.93
Giuseppe Pettiti4143.64
Nicola Cau572.30
Veronica Cimolin6428.78
Corrado Azzaro7415.43
Lorenzo Priano872.91
Alessandro Mauro9567.83